Enabling Precision Medicine in the Era of the Genome with SAP Health and Dell EMC
As a key enabler for precision medicine, genomic sequencing will soon be pervasive in many areas of healthcare. For example, we are entering an era in which all cancer patients can have their genomes sequenced to enable precision treatments tailored to the individual and the type and stage of disease.
With the advent of genome sequencing, researchers and physicians now have a critical resource to help them understand the underlying molecular mechanics and pathways of disease. Armed with fresh analytic insights, researchers can accelerate their development of personalized, patient-centered treatments and innovations, including drugs, therapies, devices and diagnostic tests. At the same time, data-driven genotypic insights integrated with phenotypic or medical records can also help physicians deepen their understanding of their patients and get patients more involved in their own healthcare, to improve prevention, diagnosis, treatment and care.
However, as we enter the “Era of the Genome,” there are significant challenges that arise from an IT transformation perspective.
To begin with, genomic data alignment and assembly require an enormous amount of computational power and temporary data storage capacity, and archival storage is orders of magnitude higher. A single genome can total hundreds of gigabytes, and in the future, physicians and researchers might want to compare the genomes and health records of millions of patients to identify causes and treatments for diseases. It is a huge challenge to get insights out of such an overwhelming amount of data that is growing exponentially — notwithstanding the new data rush from stream-based medical devices and the Internet of Things (IoT).
An End-To-End Solution for Clinical and Research Data Analysis
Dell EMC helps organizations solve the genomic data puzzle in their journey toward precision medicine with an end-to-end solution for the genomics data analysis work stream that leverages the SAP Health platform. It leverages a Dell EMC reference architecture that brings together the combined capabilities of SAP Health, a Dell EMC Isilon data lake, the Cloudera distribution of Apache™ Hadoop® and SAP Vora into SAP HANA powered by Dell EMC Ready Solutions. These posts from our Direct2DellEMC blog provide some additional context and background on our existing engagement with SAP:
– 21st Century Computing: Dell EMC, Intel and SAP power better patient outcomes
– Partners in Personalized Medicine: Dell, SAP and Intel team up to provide optimized patient results
With SAP Health, organizations can combine and analyze traditional patient data sources with clinical, research, molecular, image, social information and more. Drawing on the power of SAP HANA® and its standard-setting in-memory database, the SAP Health platform is extremely effective at generating rapid insights from huge datasets. This platform for personalized-medicine applications enables processing and real-time analysis of big medical data from various sources, all in a single system driven by SAP HANA.